Electrochemical characterization of ZnO-based transparent materials as recording electrodes for neural probes in optogenetics

In the elucidation of brain functions, neuroscience has garnered attention in realization brain-machine interfaces, deep stimulation, and artificial intelligence. Optogenetics is a biological technique used to control neural activities via optical stimulation. It one most effective approaches investigate functions. This study proposed employ transparent recording electrode enhance performance probes for optogenetics. Compared with conventional metal electrodes, electrodes have potential obtain higher signal-to-noise ratios when placed over stimulation points. To develop we ZnO-based materials good biocompatibility transparency utilization as biomedical electrodes. Considering saline main components living organisms, investigated fundamental electrochemical characteristics through impedance spectroscopy cyclic voltammetry. The results showed that nondoped ZnO Al-doped ZnO, deposited by radio frequency magnetron sputtering, exhibited broad window. An electrical double layer was found strongly act on interface between solution rather than redox reaction. addition, this reports effects crystallization dopant developed herein promising candidate optogenetics can be effectively applied devices.